The protein p53 is the product of the gene, TP53. Mutation in the TP53 gene has been associated with the pathology of several malignant cancers. TP53 is classified as a tumour-suppressor gene - it acts as a 'brake' during the cell cycle, and prevents cells from replicating too quickly. All human cells, apart from gametes… Continue reading The role of p53 in cancer
Each cell in the body divides a finite number of times. During each cell division a complex series of events takes place inside the cell, which ensures that each daughter cell is an exact genetic replica of the parent. These events are orchestrated by master genes, which produce proteins that act as gatekeepers at the… Continue reading Tumour suppressor genes and cancer
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